About Bone Modifying Agents

Bone Modifying Agents are used in the management of osteoporosis and hypercalcemia of malignancy. These agents incorporated into adjuvant therapy for metastatic cancer improve bone mineral density (BMD) and reduce the risk of fractures.

In addition, bone-modifying drugs may help reduce or lessen chronic pain over time.

Bisphosphonates block the cells that dissolve bone, called osteoclasts. They are administered intravenously (IV) every 3 to 4 weeks.

Other Bone Modifying Agents are given as an injection under the skin (called a subcutaneous injection) every 4 weeks.

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